The midfield duo, who have been struggling from thigh and hamstring injuries respectively, have made timely returns to fitness to give Reid a selection headache ahead of the fixture.
The Pilgrims boss must decide which of the pair will take the place of ex-loanee Connor Clifford in the starting line-up following the 19-year-old's return to parent-club Chelsea last week, but club captain Fletcher is likely to get the nod.
Fellow midfielder Craig Noone will be in contention after overcoming a groin problem he suffered last week.
Defender Onismor Bhasera is expected to shake off illness to make the starting line-up as the club look to extent a run of two consecutive home victories.
Source: PA
Source: PA