Patterson lashed in Argyle's match-winner against Dagenham on Good Friday, but he was later sent off after picking up a second yellow card.
That means the striker is suspended and leaves boss Reid with a vacancy in attack.
He could retain defender Kari Arnason in the unfamiliar role, however he will be hopeful Rory Fallon can shake off a groin problem.
The New Zealander was pencilled in to start against the Daggers but was forced to withdraw prior to kick-off.
Simon Walton is also a doubt after he was forced off during the second period of Friday's win and Reid will give the midfielder as long as possible to recover before making a decision.
Source: PA
Source: PA