Swansea midfielder Leon Britton, who missed the game against Newcastle with a back problem, remains sidelined.
Albert Serran, Cedric van der Gun (both hamstring) and Craig Beattie (ankle) are also out.
MATCH PREVIEW
Plymouth have won four games in 10 since Paul Mariner took over as boss - as many as they won in 19 matches before Mariner replaced Paul Sturrock. But they are still one off the bottom of the table and six points from safety.
The Pilgrims' dismal home form is a big factor in their struggle this season. They have lost more games at home and picked up fewer points than any other team in the Championship.
They now face the only side in the division to have scored as few goals as they have. Both Argyle and Swansea have netted only 27 league goals this season.
But they are also facing the only side yet to lose a Championship game in 2010. Swansea, who have been excellent at the back, are fourth in the table and unbeaten in nine matches.
MATCH FACTS
Head-to-head
• This is the 80th league meeting of Plymouth and Swansea. Each club has won 31 of the previous 79, with 17 drawn.
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• Their last three meetings have been won 1-0 by Swansea.
Plymouth
• Plymouth have gone 15 matches without a draw, which is the longest such run in the Championship.
• If selected, Jamie Mackie will be making his 100th career league appearance and Rory Fallon will face his former club.
Swansea
• Swansea have recorded eight single-goal victories in the league this season. Their other four wins were by a two-goal margin.
• They have won four and drawn five since a 1-0 home defeat against Nottingham Forest on 12 December.
• Darren Pratley is in line for his 200th club career appearance.
MOST RECENT MEETING
Swansea 1-0 Plymouth (8 December 2009)
Swansea scorer: Trundle 52.
Source: BBC Sport
Source: BBC Sport